HitPredict

Interactor 1: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Interactor 2: SCAM5 (Q8TAC9)
Secretory carrier-associated membrane protein 5 (Secretory carrier membrane protein 5) (hSCAMP5)
Gene: SCAMP5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19234194
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0016020 - membrane GO:0032588 - trans-Golgi network membrane GO:0055038 - recycling endosome membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 100 Hs			1 235
+	Hs
		261694 VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00		SCAM5_HUMAN (1-235): 2.83e-95: 279: 100.00
+	Hs
		168540 VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00		SCAM2_HUMAN (4-214): 5.6e-92: 275: 50.24
+	Hs
		168400 VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00		SCAM1_HUMAN (4-200): 1.82e-87: 264: 47.48
+	Hs
		727 VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00		A0A087WXB0_HUMAN (4-200): 8.95e-87: 261: 47.48
+	Hs
		168363 VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51		SCAM1_HUMAN (4-200): 1.82e-87: 264: 47.48
+	Hs
		168444 VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07		SCAM1_HUMAN (4-200): 1.82e-87: 264: 47.48
+	Hs
		156429 VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57		SCAM3_HUMAN (2-219): 1.45e-88: 267: 46.12
+	Hs
		731 VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07		A0A087WXB0_HUMAN (4-200): 8.95e-87: 261: 47.48