HitPredict

Interactor 1: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Interactor 2: BET1L (Q9NYM9)
BET1-like protein (Golgi SNARE with a size of 15 kDa) (GOS-15) (GS15) (Vesicle transport protein GOS15)
Gene: BET1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005829 - cytosol GO:0016020 - membrane GO:0031201 - SNARE complex GO:0042147 - retrograde transport, endosome to Golgi
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 100 Hs			1 111
+	Hs
		169474 VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		169416 VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		169594 VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		169333 SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Dm
		577224 SYB_DROME (6-97): 5.15e-29: 103: 59.78		Q7JRF1_DROME (7-106): 9.37e-26: 99.7: 15.00
+	Dm
		577258 SYB_DROME (6-97): 5.15e-29: 103: 59.78		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77
+	Dm
		1178137 Q7JYX5_DROME (6-94): 1.48e-27: 101: 23.60		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77
+	Sc
		611769 SNC2_YEAST (3-83): 9.4e-26: 93.9: 30.86		BET1_YEAST (1-105): 3.81e-26: 96.2: 16.19
+	Hs
		235129 VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Hs
		235174 VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Rn
		1144363 VAMP1_RAT (8-99): 1.05e-26: 96.6: 72.83		STX6_RAT (1-92): 1.14e-22: 90.1: 16.30
+	Sc
		611796 NYV1_YEAST (2-98): 6.05e-23: 90.4: 23.47		BET1_YEAST (1-105): 3.81e-26: 96.2: 16.19
+	Sc
		605819 SEC22_YEAST (1-97): 1.07e-21: 86.2: 18.56		BET1_YEAST (1-105): 3.81e-26: 96.2: 16.19
+	Hs
		235130 SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Hs
		212689 VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		212844 VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		212772 VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		212790 VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		212988 VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		212690 SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56