HitPredict

Interactor 1: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Interactor 2: K1C24 (Q2M2I5)
Keratin, type I cytoskeletal 24 (Cytokeratin-24) (CK-24) (Keratin-24) (K24) (Type I keratin-24)
Gene: KRT24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 525
+	Hs
		475002 UBB_HUMAN (1-76): 2.4e-30: 107: 57.90		K1C17_HUMAN (133-517): 4.06e-147: 430: 55.33
+	Hs
		531476 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		K1C13_HUMAN (129-468): 1.16e-145: 427: 59.71
+	Hs
		531369 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		K1C10_HUMAN (135-450): 1.02e-141: 422: 68.35
+	Hs
		359358 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		K1C14_HUMAN (104-515): 3.58e-118: 358: 51.70
+	Hs
		724084 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		K1C9_HUMAN (135-463): 1.36e-103: 325: 52.58
+	Hs
		318811 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		K2C75_HUMAN (2-459): 1.43e-85: 276: 24.46
+	Hs
		531578 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		K2C5_HUMAN (2-459): 6.74e-70: 236: 23.97