HitPredict

Interactor 1: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Interactor 2: BRWD3 (Q6RI45)
Bromodomain and WD repeat-containing protein 3
Gene: BRWD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 1802
+	Sc
		408323 RS31_YEAST (1-70): 3.03e-30: 105: 52.86		BDF1_YEAST (1092-1684): 8.85e-72: 257: 14.08
+	Hs
		1079568 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		FBXW7_HUMAN (395-683): 2.37e-42: 169: 12.93
+	Hs
		903105 RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14		WDR5_HUMAN (453-689): 3.34e-36: 143: 12.30
+	Hs
		903252 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		WDR5_HUMAN (453-689): 3.34e-36: 143: 12.30
+	Hs
		1079551 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		PHIP_HUMAN (1-171): 3.05e-22: 107: 7.98
+	Hs
		1079630 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		FBW1B_HUMAN (183-495): 1.87e-12: 73.9: 24.46