HitPredict

Interactor 1: G5EFZ5 (G5EFZ5)
Methylosome subunit pICln
Gene: icln-1

Interactor 2: SMD1 (Q10013)
Probable small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1)
Gene: snr-3

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19123269
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	LSM~Voldacs
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0005829 - cytosol GO:0034715 - pICln-Sm protein complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 205 Ce			1 126
+	Ce
		107955 G5EFZ5_CAEEL (1-205): 2.06e-73: 222: 100.00		SMD3_CAEEL (2-121): 2.85e-35: 120: 31.41
+	Ce
		107977 G5EG22_CAEEL (1-205): 5.95e-68: 209: 84.89		SMD3_CAEEL (2-121): 2.85e-35: 120: 31.41
+	Ce
		107976 G5EG22_CAEEL (1-205): 5.95e-68: 209: 84.89		SMD1_CAEEL (1-121): 4.68e-28: 101: 100.00
+	Dm
		55530 ICLN_DROME (1-192): 2.88e-42: 143: 16.37		Q9VTW6_DROME (1-90): 1.08e-33: 114: 35.87
+	Hs
		867409 ICLN_HUMAN (82-173): 1.28e-12: 66.4: 9.78		SMD1_HUMAN (1-96): 6.27e-35: 118: 76.04
+	Hs
		867495 ICLN_HUMAN (82-173): 1.28e-12: 66.4: 9.78		LSM4_HUMAN (1-89): 1.45e-34: 118: 25.56
+	Hs
		867411 ICLN_HUMAN (82-173): 1.28e-12: 66.4: 9.78		SMD3_HUMAN (2-105): 4.14e-33: 113: 23.08
+	Hs
		867492 ICLN_HUMAN (82-173): 1.28e-12: 66.4: 9.78		LSM2_HUMAN (1-94): 2.09e-33: 113: 34.38
+	Hs
		867458 ICLN_HUMAN (82-173): 1.28e-12: 66.4: 9.78		LSM10_HUMAN (3-100): 3.51e-30: 106: 27.55
+	Hs
		867405 ICLN_HUMAN (82-173): 1.28e-12: 66.4: 9.78		RUXF_HUMAN (3-69): 2.72e-27: 98.1: 29.85