Interactor 1: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Interactor 2: OTUB1 (Q96FW1)
Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1)
Gene: OTUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 18954305, 33665565
Identification Methods enzymatic study, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C65~ubiquitin
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0031625 - ubiquitin protein ligase binding
GO:0070062 - extracellular exosome
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 81
Hs

1 271
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024