HitPredict

Interactor 1: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Interactor 2: RHOF (Q9HBH0)
Rho-related GTP-binding protein RhoF (Rho family GTPase Rif) (Rho in filopodia)
Gene: RHOF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 211
+	Ce
		1094616 NEDD8_CAEEL (1-77): 7.56e-34: 112: 87.01		RHO1_CAEEL (21-211): 4.48e-89: 261: 49.22
+	Hs
		923947 RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14		RAC1_HUMAN (20-211): 9.06e-84: 248: 49.48
+	Hs
		120455 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		RHOD_HUMAN (5-198): 4.14e-90: 265: 52.06
+	Hs
		900357 RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14		RHOA_HUMAN (21-211): 1.51e-78: 235: 48.69
+	Hs
		474987 UBB_HUMAN (1-76): 2.4e-30: 107: 57.90		RAC1_HUMAN (20-211): 9.06e-84: 248: 49.48
+	Hs
		475199 UBB_HUMAN (1-76): 2.4e-30: 107: 57.90		RHOF_HUMAN (1-211): 5.13e-79: 237: 100.00
+	Hs
		951018 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		RHOG_HUMAN (19-211): 4.47e-79: 236: 46.11
+	Hs
		894049 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		CDC42_HUMAN (19-211): 1.19e-77: 232: 44.04
+	Hs
		436323 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		RHOC_HUMAN (21-211): 1.44e-76: 230: 49.22
+	Hs
		915586 RL40_HUMAN (1-76): 3.79e-33: 112: 57.90		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89
+	Hs
		474983 UBB_HUMAN (1-76): 2.4e-30: 107: 57.90		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89