HitPredict

Interactor 1: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33355139, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 1507
+	Hs
		903105 RS27A_HUMAN (1-77): 6.66e-37: 122: 57.14		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		903252 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		1079568 NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00		FBXW7_HUMAN (1039-1242): 6.77e-37: 152: 9.64
+	Sc
		408338 RS31_YEAST (1-70): 3.03e-30: 105: 52.86		TAF5_YEAST (1096-1284): 5.18e-13: 76: 16.10