HitPredict

Interactor 1: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Interactor 2: NUB1 (Q9Y5A7)
NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)
Gene: NUB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.963

Property	Details
Experiments	11585840, 34642328, 20101219, 16503656, 12816948, 16877356, 17549501
Identification Methods	pull down, two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 615
+	Hs
		475257 UBB_HUMAN (1-76): 2.4e-30: 107: 57.90		NUB1_HUMAN (1-615): 0: 869: 100.00
+	Dm
		547945 RS27A_DROME (1-77): 3.39e-36: 121: 57.14		Q9VBQ3_DROME (1-606): 0: 689: 27.12
+	Dm
		574852 RL40_DROME (1-76): 1.76e-33: 112: 57.90		Q9VBQ3_DROME (1-606): 0: 689: 27.12
+	Dm
		1362286 R9PY16_DROME (1-68): 1.24e-24: 94.8: 51.47		Q9VBQ3_DROME (1-606): 0: 689: 27.12
+	Zm
		5125 A0A1D6I4G6_MAIZE (2-76): 8.47e-33: 113: 84.00		A0A1D6DWJ6_MAIZE (83-612): 3.91e-170: 498: 22.70