HitPredict

Interactor 1: VAS1 (Q15904)
V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1)
Gene: ATP6AP1

Interactor 2: VPP1 (Q93050)
V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1)
Gene: ATP6V0A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

The method score is based on:

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0007035 - vacuolar acidification GO:0007042 - lysosomal lumen acidification GO:0010008 - endosome membrane and 8 others more... GO:0016020 - membrane GO:0030665 - clathrin-coated vesicle membrane GO:0030672 - synaptic vesicle membrane GO:0033176 - proton-transporting V-type ATPase complex GO:0048388 - endosomal lumen acidification GO:0070062 - extracellular exosome GO:0097401 - synaptic vesicle lumen acidification GO:1902600 - proton transmembrane transport
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	470
Hs

1	837

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024