HitPredict

Interactor 1: VAS1 (Q15904)
V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1)
Gene: ATP6AP1

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 0.60 0.675

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0007035 - vacuolar acidification
and 5 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 470
Hs

1 856
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024