HitPredict

Interactor 1: VPS72 (Q15906)
Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) (Transcription factor-like 1)
Gene: VPS72

Interactor 2: KAT5 (Q92993)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) (cPLA(2)-interacting protein)
Gene: KAT5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.746

The method score is based on:

Property Details
Experiments 29028833, 26186194, 27153538, 28514442, 33961781, 20946988, 15647280
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000786 - nucleosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035267 - NuA4 histone acetyltransferase complex
and 5 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 364
Hs

1 513
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024