HitPredict

Interactor 1: VPS72 (Q15906)
Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) (Transcription factor-like 1)
Gene: VPS72

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~YL1
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 364 Hs			1 127
+	Hs
		1079871 VPS72_HUMAN (1-364): 3.22e-143: 412: 100.00		H2B2E_HUMAN (1-127): 4.39e-54: 167: 85.83
+	Hs
		1079891 VPS72_HUMAN (1-364): 3.22e-143: 412: 100.00		H2B1H_HUMAN (5-127): 5.52e-54: 166: 85.37
+	Hs
		918388 VPS72_HUMAN (1-364): 3.22e-143: 412: 100.00		H2B1C_HUMAN (1-127): 8.19e-54: 166: 85.04
+	Hs
		1079881 VPS72_HUMAN (1-364): 3.22e-143: 412: 100.00		H2B3B_HUMAN (1-127): 8.98e-51: 158: 85.83
+	Sc
		355989 VPS72_YEAST (3-201): 3.06e-31: 127: 20.47		H2B2_YEAST (4-126): 4.46e-41: 134: 69.36