HitPredict

Interactor 1: VPS72 (Q15906)
Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) (Transcription factor-like 1)
Gene: VPS72

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.932

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 35271311, 15647280, 16230350
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, chromatography technology
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	TIP49~YL1_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription and 6 others more... GO:0035267 - NuA4 histone acetyltransferase complex GO:0042981 - regulation of apoptotic process GO:0045893 - positive regulation of DNA-templated transcription GO:0051726 - regulation of cell cycle GO:1905168 - positive regulation of double-strand break repair via homologous recombination GO:2000779 - regulation of double-strand break repair
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	364
Hs

1	456

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024