HitPredict

Interactor 1: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Interactor 2: VAMP8 (Q9BV40)
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)
Gene: VAMP8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030670 - phagocytic vesicle membrane GO:0055037 - recycling endosome GO:0055038 - recycling endosome membrane GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 100
+	Hs
		850554 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		1079324 RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		926211 RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07
+	Hs
		261649 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		VAMP4_HUMAN (7-80): 3.4e-25: 93.4: 29.73
+	Hs
		914092 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		914322 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		VAMP8_HUMAN (1-100): 2.94e-24: 89.6: 100.00
+	Hs
		913996 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07
+	Hs
		918878 RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		87580 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		C9JXZ5_HUMAN (27-100): 3.6e-20: 78.5: 100.00
+	Hs
		1079428 RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		884499 RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		850551 RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		261647 RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56		VAMP4_HUMAN (7-80): 3.4e-25: 93.4: 29.73
+	Hs
		895094 RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		895029 RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07