HitPredict

Interactor 1: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Interactor 2: NEMO (Q9Y6K9)
NF-kappa-B essential modulator (NEMO) (FIP-3) (IkB kinase-associated protein 1) (IKKAP1) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: IKBKG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 419
+	Hs
		914503 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		NEMO_HUMAN (1-419): 1.12e-52: 183: 100.00
+	Hs
		1079953 RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		914277 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		1287377 RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Mm
		914516 RB11A_MOUSE (1-218): 1.25e-91: 269: 90.37		OPTN_MOUSE (8-418): 3.76e-33: 133: 25.78
+	Hs
		884562 RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63		OPTN_HUMAN (67-418): 2.78e-38: 147: 27.25
+	Hs
		914091 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		ITSN1_HUMAN (24-403): 1.07e-30: 127: 12.15
+	Rn
		914521 RB11A_RAT (1-218): 1.25e-91: 269: 90.37		MYO5B_RAT (61-394): 8.96e-25: 109: 17.85
+	Hs
		914486 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		MYO5A_HUMAN (38-342): 1.7e-24: 108: 14.65
+	Hs
		1079976 RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00		MYO5B_HUMAN (64-394): 2.99e-18: 89.7: 16.95
+	Hs
		914453 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		MYO5B_HUMAN (64-394): 2.99e-18: 89.7: 16.95
+	Hs
		914124 RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37		MRCKA_HUMAN (32-363): 1.19e-13: 75.1: 15.89
+	Hs
		884614 RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63		MYO5B_HUMAN (64-394): 2.99e-18: 89.7: 16.95
+	Hs
		895333 RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56		MYO5A_HUMAN (38-342): 1.7e-24: 108: 14.65
+	Hs
		895123 RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56		MRCKA_HUMAN (32-363): 1.19e-13: 75.1: 15.89
+	Hs
		895213 RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56		MY18A_HUMAN (10-390): 4.23e-09: 60.8: 15.89