HitPredict

Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Interactor 2: ZCCHV (Q7Z2W4)
Zinc finger CCCH-type antiviral protein 1 (ADP-ribosyltransferase diphtheria toxin-like 13) (ARTD13) (Inactive Poly [ADP-ribose] polymerase 13) (PARP13) (Zinc finger CCCH domain-containing protein 2) (Zinc finger antiviral protein) (ZAP)
Gene: ZC3HAV1

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	24457600, 36517590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 746 Hs			1 902
+	Hs
		331835 NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03		ZCCHV_HUMAN (1-902): 0: 1277: 100.00
+	Hs
		455486 EZH2_HUMAN (1-746): 0: 862: 100.00		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20
+	Hs
		331836 NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		1188726 NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		1188821 SETD2_HUMAN (190-732): 2.07e-89: 310: 16.64		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		1188881 EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		1188822 NSD3_HUMAN (275-729): 9.41e-70: 251: 14.42		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		1188725 EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		331702 NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20
+	Hs
		455763 NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20
+	Hs
		455884 EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20
+	Hs
		455840 NSD3_HUMAN (275-729): 9.41e-70: 251: 14.42		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20
+	Hs
		975280 KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		165691 SET1A_HUMAN (611-732): 3.19e-18: 92: 38.71		PARPT_HUMAN (273-895): 0: 578: 23.82
+	Hs
		165614 SET1A_HUMAN (611-732): 3.19e-18: 92: 38.71		PARP1_HUMAN (359-885): 5.92e-142: 449: 13.20
+	Hs
		203805 SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90		PARP2_HUMAN (382-885): 1.99e-66: 235: 12.59