HitPredict

Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Interactor 2: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 746 Hs			1 306
+	Hs
		853908 EZH2_HUMAN (1-746): 0: 862: 100.00		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		1047865 EZH2_HUMAN (1-746): 0: 862: 100.00		CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15
+	Hs
		516536 EZH2_HUMAN (1-746): 0: 862: 100.00		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		1080225 EZH2_HUMAN (1-746): 0: 862: 100.00		DAZP1_HUMAN (163-285): 3.6e-21: 94.6: 21.14
+	Hs
		1031345 EZH2_HUMAN (1-746): 0: 862: 100.00		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		516645 NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Sc
		376833 SET2_YEAST (470-733): 1.22e-59: 216: 25.56		PABP_YEAST (143-260): 3.27e-19: 89.6: 20.17