Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Interactor 2: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27634302
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SET~preSET_CXC, SET~SET
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032259 - methylation
GO:0042054 - histone methyltransferase activity
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 746
Hs

1 4911
+ Hs
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+ Mm
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+ Dm
+ Hs
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+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024