HitPredict

Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Interactor 2: PDC6I (Q8WUM4)
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)
Gene: PDCD6IP

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	24457600, 36517590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 746 Hs			1 868
+	Hs
		724847 EZH2_HUMAN (1-746): 0: 862: 100.00		MYH9_HUMAN (163-716): 5.84e-59: 221: 15.01
+	Hs
		725169 EZH2_HUMAN (1-746): 0: 862: 100.00		MYH10_HUMAN (197-713): 1.83e-42: 170: 13.08
+	Hs
		998760 EZH2_HUMAN (1-746): 0: 862: 100.00		EP300_HUMAN (527-867): 6.39e-32: 136: 13.70
+	Hs
		123953 EZH2_HUMAN (1-746): 0: 862: 100.00		SPT5H_HUMAN (703-829): 2.18e-10: 66.9: 19.42
+	Hs
		165667 SET1A_HUMAN (611-732): 3.19e-18: 92: 38.71		EP300_HUMAN (527-867): 6.39e-32: 136: 13.70
+	Hs
		123917 KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54		SPT5H_HUMAN (703-829): 2.18e-10: 66.9: 19.42