HitPredict

Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Interactor 2: TCPW (Q92526)
T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (CCT-zeta-like) (Chaperonin containing T-complex polypeptide 1 subunit 6B) (TCP-1-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303)
Gene: CCT6B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 746 Hs			1 530
+	Hs
		1080275 EZH2_HUMAN (1-746): 0: 862: 100.00		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		770850 EZH2_HUMAN (1-746): 0: 862: 100.00		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		826679 EZH2_HUMAN (1-746): 0: 862: 100.00		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Mm
		945919 Q6AXH7_MOUSE (1-746): 0: 832: 96.41		TCPH_MOUSE (2-529): 0: 573: 27.24
+	Hs
		821226 EZH2_HUMAN (1-746): 0: 862: 100.00		TCPE_HUMAN (3-527): 0: 541: 30.34
+	Mm
		945980 Q6AXH7_MOUSE (1-746): 0: 832: 96.41		TCPZ_MOUSE (1-530): 0: 560: 86.60
+	Mm
		945989 Q6AXH7_MOUSE (1-746): 0: 832: 96.41		TCPG_MOUSE (3-527): 0: 552: 28.76
+	Mm
		945948 Q6AXH7_MOUSE (1-746): 0: 832: 96.41		TCPD_MOUSE (12-522): 0: 528: 29.94
+	Hs
		573276 EZH2_HUMAN (1-746): 0: 862: 100.00		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68
+	Sc
		755770 SET1_YEAST (205-733): 1.13e-84: 292: 16.01		TCPZ_YEAST (3-530): 0: 555: 54.53
+	Sc
		755775 SET1_YEAST (205-733): 1.13e-84: 292: 16.01		TCPH_YEAST (4-527): 0: 533: 25.61
+	Sc
		755768 SET1_YEAST (205-733): 1.13e-84: 292: 16.01		TCPG_YEAST (2-527): 0: 530: 27.64
+	Hs
		1296406 EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		1306682 SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10		TCPH_HUMAN (2-529): 0: 568: 27.43
+	Hs
		771045 SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10		TCPZ_HUMAN (1-530): 0: 558: 85.85
+	Hs
		826825 EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Hs
		826887 SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10		TCPG_HUMAN (3-527): 0: 551: 28.20
+	Hs
		821409 SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10		TCPE_HUMAN (3-527): 0: 541: 30.34
+	Hs
		573423 EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68
+	Hs
		573479 SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10		TCPA_HUMAN (23-523): 2.19e-67: 228: 28.68