HitPredict

Interactor 1: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Interactor 2: BAZ1A (Q9NRL2)
Bromodomain adjacent to zinc finger domain protein 1A (ATP-dependent chromatin-remodeling protein) (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (CHRAC subunit ACF1) (Williams syndrome transcription factor-related chromatin-remodeling factor 180) (WCRF180) (hWALp1)
Gene: BAZ1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27634302
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005721 - pericentric heterochromatin GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 746 Hs			1 1556
+	Mm
		102330 EZH2_MOUSE (1-746): 0: 860: 98.39		G3UWZ0_MOUSE (1-1556): 0: 1065: 87.16
+	Hs
		998760 EZH2_HUMAN (1-746): 0: 862: 100.00		EP300_HUMAN (794-1537): 2.78e-72: 270: 11.46
+	Hs
		1080166 EZH2_HUMAN (1-746): 0: 862: 100.00		PHIP_HUMAN (1179-1555): 1.3e-40: 167: 14.29
+	Hs
		1080191 EZH2_HUMAN (1-746): 0: 862: 100.00		KAT2B_HUMAN (1417-1535): 1.83e-38: 158: 26.05
+	Hs
		1017304 EZH2_HUMAN (1-746): 0: 862: 100.00		BPTF_HUMAN (1432-1534): 1.06e-33: 144: 29.13
+	Hs
		1080295 EZH2_HUMAN (1-746): 0: 862: 100.00		CECR2_HUMAN (1416-1543): 1.6e-33: 143: 28.91
+	Hs
		631440 EZH2_HUMAN (1-746): 0: 862: 100.00		BRD2_HUMAN (1369-1538): 1.74e-30: 132: 19.19
+	Hs
		1066975 EZH2_HUMAN (1-746): 0: 862: 100.00		BRD3_HUMAN (1419-1533): 1.46e-27: 122: 27.97
+	Hs
		1080085 EZH2_HUMAN (1-746): 0: 862: 100.00		PB1_HUMAN (1264-1556): 1.76e-22: 107: 15.53
+	Hs
		1080127 EZH2_HUMAN (1-746): 0: 862: 100.00		KMT2C_HUMAN (1078-1356): 7.53e-16: 86.1: 15.41
+	Hs
		631536 EZH1_HUMAN (15-745): 0: 745: 63.48		BRD2_HUMAN (1369-1538): 1.74e-30: 132: 19.19
+	Hs
		331899 NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03		BAZ2A_HUMAN (239-1535): 2.63e-131: 452: 14.33
+	Dm
		1177412 ASH1_DROME (196-732): 2.08e-99: 339: 18.55		BRDH_DROME (1052-1536): 7.73e-49: 193: 12.78
+	Hs
		331678 NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03		NSD2_HUMAN (593-1388): 3.08e-53: 207: 11.25
+	Dm
		532755 ASH1_DROME (196-732): 2.08e-99: 339: 18.55		FSH_DROME (1402-1555): 9.64e-30: 131: 24.69
+	Hs
		331723 NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03		BRD2_HUMAN (1369-1538): 1.74e-30: 132: 19.19
+	Mm
		1207357 NSD2_MOUSE (275-729): 1.45e-92: 317: 16.03		BRD4_MOUSE (1393-1552): 9.71e-27: 121: 28.74
+	Hs
		331815 NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03		BRD3_HUMAN (1419-1533): 1.46e-27: 122: 27.97
+	Hs
		1067099 NSD1_HUMAN (275-729): 6.24e-90: 311: 15.82		BRD3_HUMAN (1419-1533): 1.46e-27: 122: 27.97
+	Hs
		331900 NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03		BAZ1B_HUMAN (1210-1535): 1.53e-23: 111: 13.64