HitPredict

Interactor 1: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Interactor 2: AJUBA (Q96IF1)
LIM domain-containing protein ajuba
Gene: AJUBA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005912 - adherens junction GO:0005925 - focal adhesion and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 572 Hs			1 538
+	Hs
		1294459 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		AJUBA_HUMAN (1-538): 1.06e-96: 305: 100.00
+	Hs
		1076405 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		1076563 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		1076401 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		1076487 FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61		TRIP6_HUMAN (80-530): 6.56e-57: 199: 25.81
+	Hs
		238967 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		LPXN_HUMAN (186-528): 2.23e-47: 171: 17.82
+	Hs
		238998 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		LPXN_HUMAN (186-528): 2.23e-47: 171: 17.82
+	Hs
		238966 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		LPXN_HUMAN (186-528): 2.23e-47: 171: 17.82
+	Hs
		816247 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		LIMS1_HUMAN (292-526): 1.32e-42: 156: 19.67
+	Hs
		1080752 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		PDLI5_HUMAN (9-456): 1.16e-29: 125: 14.50
+	Hs
		823405 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		823508 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		823403 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		PAXI_HUMAN (19-459): 1.31e-29: 124: 18.72
+	Hs
		1080796 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		1080809 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		LIMD1_HUMAN (14-536): 1.42e-19: 94.3: 14.99
+	Hs
		1344047 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		PDLI7_HUMAN (1-390): 1.99e-20: 95.9: 13.89
+	Hs
		1355150 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		LIMD1_HUMAN (14-536): 1.42e-19: 94.3: 14.99
+	Hs
		63207 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		WTIP_HUMAN (392-535): 6.42e-18: 88.2: 22.67
+	Hs
		1080745 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		LPP_HUMAN (10-454): 6.46e-11: 67: 13.00