HitPredict

Interactor 1: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Interactor 2: TANC2 (Q9HCD6)
Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)
Gene: TANC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	28514442, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 572 Hs			1 1990
+	Hs
		1335965 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		TANC2_HUMAN (1-1990): 0: 1698: 100.00
+	Hs
		1044709 FHL3_HUMAN (410-544): 1.63e-09: 61.2: 28.99		TANC2_HUMAN (1-1990): 0: 1698: 100.00
+	Hs
		1080814 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		KDIS_HUMAN (780-1136): 1.42e-61: 236: 25.28
+	Hs
		1080774 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		TANC1_HUMAN (1045-1990): 4.11e-61: 234: 17.10
+	Hs
		1080712 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		ANKH1_HUMAN (843-972): 3.91e-27: 123: 27.69
+	Hs
		1021444 AJUBA_HUMAN (9-499): 2.93e-13: 74.3: 11.33		ANK3_HUMAN (892-1254): 1.05e-74: 280: 25.49
+	Hs
		823450 PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12		ANR52_HUMAN (375-999): 2.95e-57: 219: 12.61
+	Hs
		965107 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		ANK2_HUMAN (1602-1963): 1.41e-12: 75.9: 12.06
+	Hs
		1044735 FHL3_HUMAN (410-544): 1.63e-09: 61.2: 28.99		KDIS_HUMAN (780-1136): 1.42e-61: 236: 25.28
+	Hs
		823441 PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12		ANKH1_HUMAN (843-972): 3.91e-27: 123: 27.69
+	Hs
		1044642 FHL3_HUMAN (410-544): 1.63e-09: 61.2: 28.99		ANKH1_HUMAN (843-972): 3.91e-27: 123: 27.69
+	Hs
		257611 FHL2_HUMAN (468-572): 2.68e-19: 90.1: 21.91		ANR17_HUMAN (1310-1899): 1.35e-10: 69.3: 11.80
+	Hs
		816234 LIMS1_HUMAN (383-566): 1.09e-10: 65.1: 25.95		DAPK1_HUMAN (1092-1225): 5.8e-12: 73.6: 33.58