HitPredict

Interactor 1: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Interactor 2: TES (Q9UGI8)
Testin (TESS)
Gene: TES

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.853

Property	Details
Experiments	28514442, 28378594, 12695497
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 572 Hs			1 421
+	Hs
		1293409 PDLI5_HUMAN (29-568): 1.52e-63: 221: 16.24		TES_HUMAN (1-421): 2.51e-143: 416: 100.00
+	Hs
		823405 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		PAXI_HUMAN (298-421): 1.67e-35: 139: 22.58
+	Hs
		1080752 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		PDLI5_HUMAN (298-420): 1.76e-31: 128: 26.83
+	Hs
		823508 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		PAXI_HUMAN (298-421): 1.67e-35: 139: 22.58
+	Hs
		823403 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		PAXI_HUMAN (298-421): 1.67e-35: 139: 22.58
+	Hs
		1076405 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		TRIP6_HUMAN (131-365): 5.3e-21: 96.8: 14.56
+	Hs
		1076563 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		TRIP6_HUMAN (131-365): 5.3e-21: 96.8: 14.56
+	Hs
		1076401 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		TRIP6_HUMAN (131-365): 5.3e-21: 96.8: 14.56
+	Hs
		1076487 FBLI1_HUMAN (252-572): 4.13e-67: 224: 29.61		TRIP6_HUMAN (131-365): 5.3e-21: 96.8: 14.56
+	Hs
		1080796 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		PDLI7_HUMAN (358-421): 2.61e-09: 61: 26.56
+	Hs
		238967 ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00		LPXN_HUMAN (358-421): 5.43e-09: 59.4: 21.88
+	Hs
		63207 WTIP_HUMAN (196-571): 8.71e-56: 195: 28.08		TRIP6_HUMAN (131-365): 5.3e-21: 96.8: 14.56
+	Hs
		1344047 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		PDLI7_HUMAN (358-421): 2.61e-09: 61: 26.56
+	Hs
		238998 LIMD1_HUMAN (1-571): 7.16e-66: 228: 22.80		LPXN_HUMAN (358-421): 5.43e-09: 59.4: 21.88
+	Hs
		1076548 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		PDLI7_HUMAN (358-421): 2.61e-09: 61: 26.56
+	Hs
		238966 TRIP6_HUMAN (63-571): 6e-66: 224: 32.82		LPXN_HUMAN (358-421): 5.43e-09: 59.4: 21.88
+	Hs
		1293402 PDLI5_HUMAN (29-568): 1.52e-63: 221: 16.24		PDLI7_HUMAN (358-421): 2.61e-09: 61: 26.56
+	Ce
		107630 Q3S1I9_CAEEL (401-572): 5.41e-47: 168: 28.00		G5EFG1_CAEEL (301-420): 2.29e-26: 113: 22.13
+	Hs
		238992 LPXN_HUMAN (221-570): 4.84e-47: 170: 18.75		PDLI7_HUMAN (358-421): 2.61e-09: 61: 26.56