HitPredict

Interactor 1: ADRM1 (Q16186)
Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)
Gene: ADRM1

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.941

Property	Details
Experiments	27396824, 33277362, 27114451, 18497817, 20059542, 24811749
Identification Methods	pull down, x-ray crystallography, affinity chromatography technology, nuclear magnetic resonance, blue native page
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	Proteasom_Rpn13~ubiquitin, RPN13_C~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 624
+	Hs
		1081048 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Dm
		1375074 Q9W4E6_DROME (18-396): 2.05e-100: 303: 27.91		Q9VWD9_DROME (26-617): 4.15e-130: 395: 44.35
+	Hs
		1081025 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		DDI1_HUMAN (43-314): 2.92e-54: 191: 15.60
+	Hs
		1081011 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		DDI2_HUMAN (43-314): 6.26e-52: 185: 14.59
+	Hs
		924310 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		924012 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	At
		221311 RPN13_ARATH (246-395): 4.04e-32: 125: 32.03		DSK2B_ARATH (15-544): 6.1e-93: 298: 28.13
+	Dm
		547923 ADRM1_DROME (24-403): 1.81e-119: 354: 41.78		RS27A_DROME (33-103): 6.99e-13: 68.4: 33.33