HitPredict

Interactor 1: ADRM1 (Q16186)
Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)
Gene: ADRM1

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	27114451, 20059542, 16713569
Identification Methods	affinity chromatography technology, pull down, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Proteasom_Rpn13~ubiquitin, RPN13_C~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 589
+	Hs
		1081046 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Dm
		1375074 Q9W4E6_DROME (18-396): 2.05e-100: 303: 27.91		Q9VWD9_DROME (30-582): 3.32e-135: 407: 47.39
+	Hs
		1081025 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		DDI1_HUMAN (47-318): 6.39e-53: 187: 15.60
+	Hs
		1081011 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		924310 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		924012 ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	At
		221311 RPN13_ARATH (246-395): 4.04e-32: 125: 32.03		DSK2B_ARATH (19-586): 1.62e-110: 343: 32.59
+	Dm
		547923 ADRM1_DROME (24-403): 1.81e-119: 354: 41.78		RS27A_DROME (37-107): 1.11e-12: 68: 36.11
+	Pf
		1212878 Q8ILV5_PLAF7 (19-167): 1.01e-56: 188: 32.00		Q8IJS8_PLAF7 (37-351): 6.06e-38: 146: 15.30