Interactor 1: ADRM1 (Q16186)
Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)
Gene: ADRM1
Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.993 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 21516116, 28598414, 28442575, 30217970, 28198400, 32631902, 27114451, 16990800, 16906146, 20471946, 17139257, 26186194, 25702870, 28514442, 27107012, 32857986, 33961781, 34761751, 35451368 and 5 others
more... |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, x-ray crystallography, biochemical, validated two hybrid, two hybrid array, anti tag coimmunoprecipitation, two hybrid prey pooling approach, barcode fusion genetics two hybrid |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Peptidase_C12~RPN13_C, RPN13_C~UCH_C |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070628 - proteasome binding |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
