HitPredict

Interactor 1: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Interactor 2: MTUS2 (Q5JR59)
Microtubule-associated tumor suppressor candidate 2 (Cardiac zipper protein) (Microtubule plus-end tracking protein TIP150) (Tracking protein of 150 kDa)
Gene: MTUS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.50	0.638

Property	Details
Experiments	32296183, 28514442, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 474 Hs			1 1369
+	Hs
		1078835 ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38		MTUS2_HUMAN (1-1369): 0: 1143: 100.00
+	Hs
		1078830 CCDC6_HUMAN (1-474): 2.18e-48: 174: 100.00		ITSN1_HUMAN (748-1251): 2.26e-22: 107: 14.09
+	Hs
		1078919 ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38		ITSN2_HUMAN (755-1327): 1.16e-31: 137: 14.65
+	Hs
		1078828 ITSN1_HUMAN (14-474): 1.6e-22: 103: 11.38		ITSN1_HUMAN (748-1251): 2.26e-22: 107: 14.09
+	Hs
		724810 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		ROCK1_HUMAN (672-1362): 3.23e-31: 135: 11.70
+	Hs
		1201957 TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46		MRCKB_HUMAN (1175-1367): 5.39e-15: 82.9: 8.70
+	Rn
		222476 MRCKB_RAT (23-351): 1.72e-21: 100: 15.25		MRCKA_RAT (602-1112): 1.36e-14: 81.4: 6.54
+	Hs
		1051363 DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02		NIN_HUMAN (992-1353): 2.45e-14: 80.6: 18.36
+	Rn
		1186812 MRCKB_RAT (23-351): 1.72e-21: 100: 15.25		MRCKB_RAT (1175-1369): 2.61e-14: 80.6: 12.87
+	Hs
		1051509 DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02		MTUS1_HUMAN (600-1071): 1.41e-12: 74.9: 7.72
+	Hs
		1137917 MRCKB_HUMAN (23-351): 2.44e-20: 96.6: 14.57		MRCKA_HUMAN (1190-1369): 6.05e-11: 69.5: 13.98
+	Hs
		724687 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		MYH10_HUMAN (928-1347): 4.52e-17: 89.6: 16.17
+	Hs
		725035 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		MYO5C_HUMAN (989-1334): 1.01e-13: 78.7: 19.18
+	Hs
		1268126 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		MRCKB_HUMAN (1175-1367): 5.39e-15: 82.9: 8.70
+	Mm
		93570 MYH9_MOUSE (2-406): 4.45e-12: 70.8: 7.14		DESP_MOUSE (986-1334): 6.74e-13: 76: 19.23
+	Sc
		630950 USO1_YEAST (55-329): 2.37e-12: 71.5: 19.42		USO1_YEAST (923-1329): 2.08e-12: 74.5: 20.76
+	Hs
		1268099 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		MYO5C_HUMAN (989-1334): 1.01e-13: 78.7: 19.18
+	Hs
		724686 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70
+	Hs
		724943 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		MYH9_HUMAN (683-1130): 6.12e-12: 72.9: 9.70
+	Pf
		1211827 Q8I5X5_PLAF7 (80-339): 4.68e-12: 70.7: 19.44		Q8I5X5_PLAF7 (1129-1357): 2.73e-10: 67.5: 12.45