HitPredict

Interactor 1: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 474 Hs			1 2346
+	Mm
		88361 CCDC6_MOUSE (1-474): 8.65e-43: 159: 93.07		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Mm
		1194560 KI21B_MOUSE (1-374): 6.9e-29: 122: 19.31		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Hs
		969585 DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02		CENPE_HUMAN (1-1839): 1.04e-60: 234: 11.33
+	Hs
		724994 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73
+	Hs
		166706 DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02		CE290_HUMAN (10-915): 3.83e-20: 100: 9.92
+	Hs
		1051424 DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02		CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90
+	Mm
		139891 DCTN1_MOUSE (7-361): 3.79e-22: 102: 13.94		CE290_MOUSE (1-666): 3.82e-13: 77.7: 10.25
+	Hs
		528356 MYH6_HUMAN (20-389): 4.46e-10: 64.2: 9.00		MYH6_HUMAN (1376-2333): 1.06e-22: 109: 8.98
+	Hs
		148534 CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78		CENPF_HUMAN (1261-2312): 1.38e-21: 105: 10.69
+	Hs
		724687 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		MYH10_HUMAN (1099-2077): 1.03e-18: 96.2: 11.20
+	Hs
		724976 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90
+	Hs
		725097 MYH11_HUMAN (54-323): 1.64e-09: 62.6: 17.07		MYH10_HUMAN (1099-2077): 1.03e-18: 96.2: 11.20
+	Hs
		148461 CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78		MYH10_HUMAN (1099-2077): 1.03e-18: 96.2: 11.20
+	Hs
		148466 CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78		MYH11_HUMAN (31-473): 4.26e-15: 84.3: 11.74
+	Hs
		724686 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Hs
		724943 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Hs
		148460 CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Dm
		1303379 MYSN_DROME (33-428): 2.04e-10: 65.4: 9.85		MYSN_DROME (934-1593): 1.19e-09: 66.1: 11.46
+	Hs
		148359 CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		502901 MYH6_HUMAN (20-389): 4.46e-10: 64.2: 9.00		MYH3_HUMAN (1-361): 4.36e-09: 64.2: 10.90