HitPredict

Interactor 1: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Interactor 2: LRSM1 (Q6UWE0)
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)
Gene: LRSAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	32296183, 38580884, unassigned1304
Identification Methods	two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 723
+	Hs
		1051445 DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02		LGR4_HUMAN (4-364): 1.95e-42: 167: 18.21
+	Hs
		1315178 MRCKB_HUMAN (23-351): 2.44e-20: 96.6: 14.57		LGR4_HUMAN (4-364): 1.95e-42: 167: 18.21
+	Hs
		1122642 CC157_HUMAN (40-462): 3.58e-20: 95.9: 13.21		LGR4_HUMAN (4-364): 1.95e-42: 167: 18.21
+	Hs
		724996 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		LGR4_HUMAN (4-364): 1.95e-42: 167: 18.21
+	Hs
		728512 MYH11_HUMAN (54-323): 1.64e-09: 62.6: 17.07		LGR4_HUMAN (4-364): 1.95e-42: 167: 18.21
+	Hs
		725235 MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39		LGR4_HUMAN (4-364): 1.95e-42: 167: 18.21
+	Hs
		148800 CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78		SCRIB_HUMAN (31-234): 3.51e-37: 152: 24.51