HitPredict

Interactor 1: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	25885523, 23108047
Identification Methods	affinity chromatography technology, enzymatic study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 707
+	Hs
		1263249 RUFY2_HUMAN (59-346): 8.08e-24: 106: 19.87		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		1051392 DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		1281519 MRCKB_HUMAN (23-351): 2.44e-20: 96.6: 14.57		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		724952 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		1268063 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		1068625 PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		725215 MYH10_HUMAN (2-333): 9.28e-09: 60.4: 10.39		FBXW7_HUMAN (1-707): 0: 571: 100.00
+	Hs
		792983 DCTN1_HUMAN (2-361): 1.64e-21: 100: 14.02		LIS1_HUMAN (457-706): 3.92e-66: 225: 27.08
+	Bt
		60990 A5PKJ3_BOVIN (2-361): 9.82e-21: 97.8: 13.76		LIS1_BOVIN (457-706): 2.49e-66: 226: 27.08
+	Hs
		903399 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		148610 CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		903240 PLEC_HUMAN (67-346): 2.74e-09: 61.9: 11.79		WDR5_HUMAN (570-706): 2.64e-27: 115: 23.02
+	Hs
		728492 MYH11_HUMAN (54-323): 1.64e-09: 62.6: 17.07		POC1A_HUMAN (459-659): 7.29e-18: 88.6: 27.96