HitPredict

Interactor 1: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38580884
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 474 Hs			1 729
+	Hs
		1150633 MRCKG_HUMAN (1-433): 4.02e-31: 129: 15.49		TBK1_HUMAN (1-729): 0: 564: 100.00
+	Hs
		1201936 TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46		TBK1_HUMAN (1-729): 0: 564: 100.00
+	Hs
		1050233 TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		158500 TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46		IKKB_HUMAN (9-727): 1.01e-139: 430: 18.98
+	Hs
		724823 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		167576 TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Hs
		1201957 TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46		MRCKB_HUMAN (6-700): 1.77e-108: 364: 16.10
+	Hs
		1137917 MRCKB_HUMAN (23-351): 2.44e-20: 96.6: 14.57		MRCKA_HUMAN (6-698): 6.44e-109: 365: 17.31
+	Rn
		222476 MRCKB_RAT (23-351): 1.72e-21: 100: 15.25		MRCKA_RAT (6-698): 5.51e-107: 360: 17.45
+	Hs
		167486 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Rn
		1186812 MRCKB_RAT (23-351): 1.72e-21: 100: 15.25		MRCKB_RAT (6-700): 1.94e-103: 349: 15.53
+	Hs
		167488 MYH11_HUMAN (54-323): 1.64e-09: 62.6: 17.07		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Hs
		625176 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		1268126 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		MRCKB_HUMAN (6-700): 1.77e-108: 364: 16.10
+	Hs
		725010 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		SIK2_HUMAN (9-719): 1.2e-110: 359: 15.54
+	Hs
		625530 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		528368 MYH6_HUMAN (20-389): 4.46e-10: 64.2: 9.00		CDK3_HUMAN (6-309): 7.85e-116: 352: 20.20
+	Hs
		724967 MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78		MARK4_HUMAN (9-344): 1.37e-86: 290: 24.48
+	Hs
		1268074 MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87		MARK4_HUMAN (9-344): 1.37e-86: 290: 24.48
+	Dm
		1365099 Q9W3V2_DROME (52-329): 1.43e-09: 62.6: 22.33		IKKB_DROME (1-316): 1.37e-24: 111: 30.29