Interactor 1: NF2L2 (Q16236)
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Gene: NFE2L2

Interactor 2: E2AK3 (Q9NZJ5)
Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK)
Gene: EIF2AK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 0.60 0.527

The method score is based on:

Property Details
Experiments 14517290
Identification Methods two hybrid, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression
GO:0030968 - endoplasmic reticulum unfolded protein response
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 605
Hs

1 1116
+ Hs
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

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Last updated: 15 Jul 2024