HitPredict

Interactor 1: NF2L2 (Q16236)
Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nrf-2) (HEBP1) (Nuclear factor, erythroid derived 2, like 2)
Gene: NFE2L2

Interactor 2: ELF5 (Q9UKW6)
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)
Gene: ELF5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	32911434
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 605 Hs			1 265
+	Hs
		1081247 NF2L2_HUMAN (1-605): 0: 560: 100.00		ELF4_HUMAN (1-264): 3.88e-68: 224: 21.17
+	Hs
		692142 NF2L2_HUMAN (1-605): 0: 560: 100.00		ELF1_HUMAN (116-261): 3.1e-44: 159: 28.57
+	Hs
		794546 NF2L2_HUMAN (1-605): 0: 560: 100.00		ETV4_HUMAN (112-260): 1.52e-40: 147: 24.50
+	Hs
		840436 NF2L2_HUMAN (1-605): 0: 560: 100.00		ETV1_HUMAN (117-260): 3.14e-40: 146: 29.05
+	Hs
		542746 NF2L2_HUMAN (1-605): 0: 560: 100.00		ETS2_HUMAN (1-173): 3.97e-39: 143: 17.03
+	Hs
		584250 NF2L2_HUMAN (1-605): 0: 560: 100.00		ELK1_HUMAN (172-257): 7.84e-39: 141: 42.53
+	Hs
		944616 NF2L2_HUMAN (1-605): 0: 560: 100.00		ELF3_HUMAN (15-192): 3.28e-26: 107: 14.61
+	Hs
		781635 NF2L2_HUMAN (1-605): 0: 560: 100.00		ETV6_HUMAN (175-255): 1.19e-14: 75.1: 45.12
+	Hs
		1083924 NFE2_HUMAN (183-603): 8.43e-60: 205: 33.02		ELF5_HUMAN (1-265): 1.43e-113: 329: 100.00
+	Mm
		450544 JUNB_MOUSE (218-576): 1.79e-64: 217: 17.49		SPI1_MOUSE (11-259): 2.87e-52: 173: 22.10
+	Hs
		401381 JUN_HUMAN (240-572): 5.59e-55: 191: 13.61		SPI1_HUMAN (11-259): 4.68e-59: 190: 23.95
+	Mm
		404116 JUN_MOUSE (240-572): 2.12e-54: 189: 14.37		SPI1_MOUSE (11-259): 2.87e-52: 173: 22.10
+	Hs
		401498 JUN_HUMAN (240-572): 5.59e-55: 191: 13.61		ELF1_HUMAN (116-261): 3.1e-44: 159: 28.57
+	Hs
		566729 JUNB_HUMAN (218-576): 2.14e-51: 182: 17.94		ELF1_HUMAN (116-261): 3.1e-44: 159: 28.57
+	Hs
		401586 JUN_HUMAN (240-572): 5.59e-55: 191: 13.61		ETV4_HUMAN (112-260): 1.52e-40: 147: 24.50
+	Hs
		401653 JUN_HUMAN (240-572): 5.59e-55: 191: 13.61		ETV1_HUMAN (117-260): 3.14e-40: 146: 29.05
+	Hs
		401352 JUN_HUMAN (240-572): 5.59e-55: 191: 13.61		ETS2_HUMAN (1-173): 3.97e-39: 143: 17.03
+	Hs
		401313 JUN_HUMAN (240-572): 5.59e-55: 191: 13.61		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		401351 JUN_HUMAN (240-572): 5.59e-55: 191: 13.61		ETS1_HUMAN (22-167): 3.12e-27: 110: 17.69
+	Hs
		541971 ATF2_HUMAN (250-573): 9.16e-40: 154: 12.99		ETS1_HUMAN (22-167): 3.12e-27: 110: 17.69