Interactor 1: CNGA3 (Q16281)
Cyclic nucleotide-gated channel alpha-3 (CNG channel alpha-3) (CNG-3) (CNG3) (Cone photoreceptor cGMP-gated channel subunit alpha-3)
Gene: CNGA3

Interactor 2: CNGB3 (Q9NQW8)
Cyclic nucleotide-gated channel beta-3 (CNG channel beta-3) (Cone photoreceptor cGMP-gated channel subunit beta) (Cyclic nucleotide-gated cation channel beta-3) (Cyclic nucleotide-gated cation channel modulatory subunit)
Gene: CNGB3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15223812
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains cNMP_binding~cNMP_binding, Ion_trans~cNMP_binding, Ion_trans~Ion_trans
Common GO terms GO:0005222 - intracellularly cAMP-activated cation channel activity
GO:0005223 - intracellularly cGMP-activated cation channel activity
GO:0005886 - plasma membrane
GO:0006812 - monoatomic cation transport
GO:0007165 - signal transduction
and 6 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 694
Hs

1 809
+ Bt
+ Hs
+ Hs
+ Ce
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ At
+ Mm
+ Mm
+ At
+ At
+ Hs
+ At
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024