Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: DOK6 (Q6PKX4)
Docking protein 6 (Downstream of tyrosine kinase 6)
Gene: DOK6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.766

The method score is based on:

Property Details
Experiments 20565848
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr
Common GO terms GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 839
Hs

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Last updated: 15 Jul 2024