HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: MON2 (Q7Z3U7)
Protein MON2 homolog (Protein SF21)
Gene: MON2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 839 Hs			1 1717
+	Hs
		385078 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		MON2_HUMAN (1-1717): 0: 1894: 100.00
+	Hs
		601539 FGFR2_HUMAN (203-838): 1.97e-168: 510: 24.89		MON2_HUMAN (1-1717): 0: 1894: 100.00
+	Hs
		508080 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		MON2_HUMAN (1-1717): 0: 1894: 100.00
+	Hs
		435680 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		MON2_HUMAN (1-1717): 0: 1894: 100.00
+	Hs
		385813 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		BIG1_HUMAN (173-398): 5.55e-12: 73.4: 16.02
+	Hs
		385258 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		GBF1_HUMAN (23-246): 5.4e-11: 70.4: 15.51
+	Hs
		411481 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		CYH2_HUMAN (250-483): 1.69e-59: 212: 15.26
+	Hs
		212302 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		CYH3_HUMAN (253-557): 1.02e-56: 204: 11.93
+	Hs
		435666 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		BIG3_HUMAN (17-369): 2.33e-46: 186: 18.04
+	Rn
		94357 INSR_RAT (513-824): 3.31e-62: 230: 38.80		F1M8X9_RAT (968-1342): 4.53e-34: 145: 15.08