HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: DJC10 (Q8IXB1)
DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr)
Gene: DNAJC10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001933 - negative regulation of protein phosphorylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 839 Hs			1 793
+	Hs
		385136 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		DJC10_HUMAN (1-793): 0: 609: 100.00
+	Hs
		1081655 NTRK3_HUMAN (1-839): 0: 671: 100.00		DJC16_HUMAN (18-249): 6.4e-64: 230: 30.83
+	Hs
		1067715 NTRK3_HUMAN (1-839): 0: 671: 100.00		PDIA6_HUMAN (135-451): 3.77e-40: 155: 16.62
+	Hs
		531844 NTRK3_HUMAN (1-839): 0: 671: 100.00		PDIA4_HUMAN (153-643): 4.32e-35: 143: 13.67
+	Hs
		1081636 NTRK3_HUMAN (1-839): 0: 671: 100.00		DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78
+	Hs
		384875 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		PDIA6_HUMAN (135-451): 3.77e-40: 155: 16.62
+	Hs
		384191 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		PDIA4_HUMAN (153-643): 4.32e-35: 143: 13.67
+	Hs
		507820 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		PDIA4_HUMAN (153-643): 4.32e-35: 143: 13.67
+	Hs
		384339 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		PDIA3_HUMAN (235-674): 4.71e-27: 118: 13.24
+	Hs
		385658 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78
+	Hs
		385177 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		TXND5_HUMAN (687-793): 2.4e-20: 96.6: 25.00
+	Hs
		531720 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		PDIA4_HUMAN (153-643): 4.32e-35: 143: 13.67
+	Hs
		609590 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		DNJB9_HUMAN (19-128): 4.03e-16: 80.1: 40.00
+	Hs
		384104 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		PDIA1_HUMAN (86-231): 1.07e-10: 66.9: 18.00
+	Hs
		607891 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		PDIA3_HUMAN (235-674): 4.71e-27: 118: 13.24
+	Hs
		608166 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78
+	Hs
		423118 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		PDIA1_HUMAN (86-231): 1.07e-10: 66.9: 18.00
+	Hs
		608165 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		DNJB9_HUMAN (19-128): 4.03e-16: 80.1: 40.00
+	Hs
		434126 RET_HUMAN (282-837): 1.5e-108: 360: 25.76		PDIA4_HUMAN (153-643): 4.32e-35: 143: 13.67
+	Hs
		434302 RET_HUMAN (282-837): 1.5e-108: 360: 25.76		DJB11_HUMAN (19-108): 1.04e-22: 102: 47.78