HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: EHBP1 (Q8NDI1)
EH domain-binding protein 1
Gene: EHBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 839 Hs			1 1231
+	Hs
		508107 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		EHBP1_HUMAN (1-1231): 0: 651: 100.00
+	Hs
		608048 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		EHBP1_HUMAN (1-1231): 0: 651: 100.00
+	Hs
		411443 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		EHBP1_HUMAN (1-1231): 0: 651: 100.00
+	Hs
		435697 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		EHBP1_HUMAN (1-1231): 0: 651: 100.00
+	Hs
		384981 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		MRCKA_HUMAN (542-1224): 3.57e-81: 295: 16.02
+	Hs
		384183 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		ACTN1_HUMAN (309-1098): 4.99e-80: 284: 12.94
+	Hs
		211458 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		ACTN4_HUMAN (309-1100): 7.04e-73: 263: 12.41
+	Hs
		384662 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		SPTB2_HUMAN (440-1228): 6.16e-69: 257: 13.85
+	Hs
		609206 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		UTRN_HUMAN (307-1230): 1.04e-67: 254: 13.25
+	Hs
		507905 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		UTRN_HUMAN (307-1230): 1.04e-67: 254: 13.25
+	Hs
		607915 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		UTRN_HUMAN (307-1230): 1.04e-67: 254: 13.25
+	Mm
		1149117 PTK7_MOUSE (212-394): 3.12e-10: 66.3: 17.35		EHBP1_MOUSE (1-1231): 0: 628: 87.04
+	Hs
		385162 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		MILK1_HUMAN (1076-1218): 3.08e-11: 70.1: 32.87
+	Hs
		508077 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		MICA3_HUMAN (1029-1214): 2.92e-12: 73.9: 32.46
+	Hs
		508099 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		MILK1_HUMAN (1076-1218): 3.08e-11: 70.1: 32.87
+	Hs
		608045 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		MILK1_HUMAN (1076-1218): 3.08e-11: 70.1: 32.87
+	Hs
		211691 ALK_HUMAN (513-816): 2.78e-59: 222: 39.03		ACTN4_HUMAN (309-1100): 7.04e-73: 263: 12.41
+	Rn
		102506 INSR_RAT (513-824): 3.31e-62: 230: 38.80		UTRN_RAT (307-1227): 1.02e-66: 251: 14.39
+	Rn
		88607 INSR_RAT (513-824): 3.31e-62: 230: 38.80		D3ZGN7_RAT (432-623): 1.09e-36: 153: 28.72