HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: HS105 (Q92598)
Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) (Heat shock protein family H member 1)
Gene: HSPH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 839 Hs			1 858
+	Hs
		320862 NTRK3_HUMAN (1-839): 0: 671: 100.00		HS74L_HUMAN (1-858): 0: 953: 57.46
+	Hs
		385266 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		HS105_HUMAN (1-858): 0: 1004: 100.00
+	Hs
		320790 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		HS74L_HUMAN (1-858): 0: 953: 57.46
+	Hs
		320811 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		HS74L_HUMAN (1-858): 0: 953: 57.46
+	Hs
		320803 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		HS74L_HUMAN (1-858): 0: 953: 57.46
+	Hs
		384373 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		HSP74_HUMAN (1-858): 0: 917: 60.98
+	Hs
		609191 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		HSP74_HUMAN (1-858): 0: 917: 60.98
+	Hs
		1081658 NTRK3_HUMAN (1-839): 0: 671: 100.00		HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41
+	Hs
		385786 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41
+	Hs
		609631 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41
+	Hs
		508291 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41
+	Hs
		608207 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41
+	Hs
		384163 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		HSP7C_HUMAN (489-709): 2.48e-32: 135: 11.26
+	Hs
		384372 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		HS71L_HUMAN (586-716): 7.63e-31: 131: 19.70
+	Hs
		503438 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		HSP7C_HUMAN (489-709): 2.48e-32: 135: 11.26
+	Hs
		434320 RET_HUMAN (282-837): 1.5e-108: 360: 25.76		HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41
+	Hs
		384219 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		HSP76_HUMAN (604-707): 8.59e-27: 118: 22.86
+	Hs
		507880 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		HS71L_HUMAN (586-716): 7.63e-31: 131: 19.70
+	Hs
		507836 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		HSP76_HUMAN (604-707): 8.59e-27: 118: 22.86
+	Hs
		1088158 DDR2_HUMAN (527-824): 2.05e-70: 250: 43.30		HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41