HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: STAM1 (Q92783)
Signal transducing adapter molecule 1 (STAM-1)
Gene: STAM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 839 Hs			1 540
+	Hs
		277073 NTRK3_HUMAN (1-839): 0: 671: 100.00		STAM2_HUMAN (1-533): 8.53e-122: 369: 54.65
+	Hs
		277074 NTRK2_HUMAN (6-839): 0: 557: 52.87		STAM2_HUMAN (1-533): 8.53e-122: 369: 54.65
+	Hs
		385279 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		STAM1_HUMAN (1-518): 1.32e-126: 382: 100.00
+	Hs
		1081629 NTRK3_HUMAN (1-839): 0: 671: 100.00		GGA3_HUMAN (1-530): 3.3e-63: 221: 15.64
+	Hs
		276985 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		STAM2_HUMAN (1-533): 8.53e-122: 369: 54.65
+	Hs
		241132 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		TOM1_HUMAN (6-454): 3.66e-69: 232: 16.81
+	Hs
		160014 NTRK3_HUMAN (1-839): 0: 671: 100.00		HGS_HUMAN (84-540): 8.62e-15: 79.4: 13.50
+	Hs
		924601 NTRK3_HUMAN (1-839): 0: 671: 100.00		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		385624 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		GGA3_HUMAN (1-530): 3.3e-63: 221: 15.64
+	Rn
		88616 NTRK1_RAT (58-839): 1.52e-171: 517: 47.78		D3ZHG8_RAT (1-534): 2.87e-61: 215: 14.78
+	Hs
		385689 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		GGA1_HUMAN (2-526): 3.1e-56: 201: 14.00
+	Hs
		385688 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		GGA2_HUMAN (2-522): 9.09e-56: 199: 17.07
+	Rn
		1144355 NTRK2_RAT (6-839): 0: 557: 52.88		HGS_RAT (84-540): 8.24e-15: 79.4: 13.31
+	Hs
		160015 NTRK2_HUMAN (6-839): 0: 557: 52.87		HGS_HUMAN (84-540): 8.62e-15: 79.4: 13.50
+	Mm
		546322 NTRK2_MOUSE (6-839): 0: 555: 53.29		HGS_MOUSE (84-540): 2.18e-13: 75.2: 13.12
+	Hs
		924603 NTRK2_HUMAN (6-839): 0: 557: 52.87		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Hs
		159837 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		HGS_HUMAN (84-540): 8.62e-15: 79.4: 13.50
+	Hs
		159889 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		HGS_HUMAN (84-540): 8.62e-15: 79.4: 13.50
+	Hs
		384619 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		GRB2_HUMAN (215-265): 2.32e-13: 71.2: 54.90
+	Rn
		728442 NTRK1_RAT (58-839): 1.52e-171: 517: 47.78		GRB2_RAT (215-265): 2.32e-13: 71.2: 54.90