HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: DNJA3 (Q96EY1)
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
Gene: DNAJA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 839 Hs			1 480
+	Hs
		385330 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		609471 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		508145 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		681463 NTRK3_HUMAN (1-839): 0: 671: 100.00		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243425 NTRK3_HUMAN (1-839): 0: 671: 100.00		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		608081 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		384352 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243251 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		507875 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243277 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		243293 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		411469 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		435729 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		243261 RET_HUMAN (282-837): 1.5e-108: 360: 25.76		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		681409 ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		411313 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		435551 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243254 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		243262 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		243669 ALK_HUMAN (513-816): 2.78e-59: 222: 39.03		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38