HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: DDRGK (Q96HY6)
DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1)
Gene: DDRGK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008284 - positive regulation of cell population proliferation GO:0010628 - positive regulation of gene expression GO:0030335 - positive regulation of cell migration
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 839 Hs			1 314
+	Hs
		508150 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		434262 RET_HUMAN (282-837): 1.5e-108: 360: 25.76		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		968458 ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		411470 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		435731 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		1294127 ALK_HUMAN (513-816): 2.78e-59: 222: 39.03		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00