HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: FNBP1 (Q96RU3)
Formin-binding protein 1 (Formin-binding protein 17) (hFBP17)
Gene: FNBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 839 Hs			1 617
+	Hs
		1001578 NTRK3_HUMAN (1-839): 0: 671: 100.00		FCHO2_HUMAN (3-579): 2.4e-52: 194: 14.75
+	Hs
		508156 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		FNBP1_HUMAN (1-617): 1.21e-118: 367: 100.00
+	Hs
		508051 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		FBP1L_HUMAN (1-617): 4.85e-111: 347: 53.96
+	Hs
		608003 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		FBP1L_HUMAN (1-617): 4.85e-111: 347: 53.96
+	Hs
		1081647 NTRK3_HUMAN (1-839): 0: 671: 100.00		PACN2_HUMAN (179-607): 1.4e-23: 106: 11.26
+	Hs
		1083896 NTRK2_HUMAN (6-839): 0: 557: 52.87		PPIP2_HUMAN (3-328): 3.23e-63: 213: 18.60
+	Hs
		297957 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		FCSD2_HUMAN (9-617): 5.93e-72: 247: 13.30
+	Hs
		253302 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		SRGP2_HUMAN (6-510): 1.26e-55: 205: 14.36
+	Hs
		508201 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		PPIP2_HUMAN (3-328): 3.23e-63: 213: 18.60
+	Hs
		253307 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		SRGP2_HUMAN (6-510): 1.26e-55: 205: 14.36
+	Hs
		507966 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		FCHO2_HUMAN (3-579): 2.4e-52: 194: 14.75
+	Hs
		608135 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		PPIP2_HUMAN (3-328): 3.23e-63: 213: 18.60
+	Hs
		1083909 NTRK2_HUMAN (6-839): 0: 557: 52.87		PACN2_HUMAN (179-607): 1.4e-23: 106: 11.26
+	Hs
		607952 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		FCHO2_HUMAN (3-579): 2.4e-52: 194: 14.75
+	Hs
		508265 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		PACN2_HUMAN (179-607): 1.4e-23: 106: 11.26
+	Hs
		508022 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		ITSN1_HUMAN (533-615): 2.01e-14: 79.1: 18.07
+	Hs
		608196 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		PACN2_HUMAN (179-607): 1.4e-23: 106: 11.26
+	Hs
		508089 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		NOSTN_HUMAN (403-607): 2.23e-09: 62.2: 17.84
+	Hs
		607984 FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57		ITSN1_HUMAN (533-615): 2.01e-14: 79.1: 18.07
+	Hs
		253341 ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56		SRGP2_HUMAN (6-510): 1.26e-55: 205: 14.36