HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: TBB6 (Q9BUF5)
Tubulin beta-6 chain (Tubulin beta class V)
Gene: TUBB6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 839 Hs			1 446
+	Hs
		384794 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		TBB3_HUMAN (1-446): 0: 727: 92.38
+	Hs
		385445 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		TBB6_HUMAN (1-446): 0: 720: 100.00
+	Hs
		384107 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		TBB5_HUMAN (1-429): 0: 719: 92.54
+	Hs
		384633 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		TBB4B_HUMAN (1-427): 0: 717: 92.74
+	Hs
		385452 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		TBB2B_HUMAN (1-430): 0: 717: 92.79
+	Hs
		508174 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		TBB6_HUMAN (1-446): 0: 720: 100.00
+	Hs
		381109 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		TBB4A_HUMAN (1-427): 0: 713: 93.44
+	Hs
		968471 ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56		TBB6_HUMAN (1-446): 0: 720: 100.00
+	Hs
		537737 INSRR_HUMAN (513-820): 1.33e-62: 231: 40.84		TBB3_HUMAN (1-446): 0: 727: 92.38
+	Hs
		411272 INSR_HUMAN (513-824): 1.34e-64: 238: 39.43		TBB5_HUMAN (1-429): 0: 719: 92.54
+	Hs
		435747 IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16		TBB6_HUMAN (1-446): 0: 720: 100.00
+	Hs
		934024 ALK_HUMAN (513-816): 2.78e-59: 222: 39.03		TBB4B_HUMAN (1-427): 0: 717: 92.74