HitPredict

Interactor 1: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Interactor 2: GBB4 (Q9HAV0)
Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)
Gene: GNB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 839 Hs			1 340
+	Hs
		921579 NTRK3_HUMAN (1-839): 0: 671: 100.00		GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00
+	Hs
		920979 NTRK2_HUMAN (6-839): 0: 557: 52.87		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		384615 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		507938 FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		384438 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		LIS1_HUMAN (259-340): 5.34e-20: 92: 23.17
+	Hs
		384596 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		WDR5_HUMAN (263-340): 5.61e-19: 88.1: 23.08
+	Hs
		609202 FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73		LIS1_HUMAN (259-340): 5.34e-20: 92: 23.17
+	Hs
		196939 NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75		PRP4_HUMAN (51-253): 3.65e-11: 65.9: 24.88
+	Rn
		192655 INSR_RAT (513-824): 3.31e-62: 230: 38.80		GBB4_RAT (1-340): 6.87e-104: 309: 97.06
+	Hs
		789108 FRK_HUMAN (533-814): 5.68e-57: 205: 37.23		GBB1_HUMAN (1-340): 1.71e-106: 316: 90.88
+	Hs
		994668 DDR1_HUMAN (535-824): 9.4e-68: 244: 43.63		SNR40_HUMAN (130-340): 1.94e-58: 194: 24.77
+	Hs
		196966 FRK_HUMAN (533-814): 5.68e-57: 205: 37.23		PRP4_HUMAN (51-253): 3.65e-11: 65.9: 24.88