Interactor 1: LTOR4 (Q0VGL1)
Ragulator complex protein LAMTOR4 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4) [Cleaved into: Ragulator complex protein LAMTOR4, N-terminally processed]
Gene: LAMTOR4

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.699

The method score is based on:

Property Details
Experiments 33961781, 25561175, 22980980, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0031902 - late endosome membrane
GO:0032008 - positive regulation of TOR signaling
GO:0038202 - TORC1 signaling
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 99
Hs

1 161
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025