HitPredict

Interactor 1: GRIK5 (Q16478)
Glutamate receptor ionotropic, kainate 5 (GluK5) (Excitatory amino acid receptor 2) (EAA2) (Glutamate receptor KA-2) (KA2)
Gene: GRIK5

Interactor 2: DLG3 (Q92796)
Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR)
Gene: DLG3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9808460
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0098839 - postsynaptic density membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 980 Hs			1 817
+	Hs
		1022366 GRIK2_HUMAN (7-892): 0: 862: 43.86		DLG3_HUMAN (1-817): 0: 713: 100.00
+	Mm
		620881 GRIA1_MOUSE (1-902): 0: 786: 33.77		DLG3_MOUSE (1-817): 0: 689: 95.05
+	Hs
		1021483 GRIK2_HUMAN (7-892): 0: 862: 43.86		DLG1_HUMAN (13-817): 0: 586: 63.90
+	Rn
		585151 GRIA1_RAT (1-902): 0: 788: 33.77		DLG1_RAT (3-817): 0: 578: 61.42
+	Hs
		786696 GRIA1_HUMAN (1-902): 0: 777: 33.77		DLG1_HUMAN (13-817): 0: 586: 63.90
+	Hs
		942350 GRIK5_HUMAN (1-980): 0: 908: 100.00		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Mm
		1142982 GRIK5_MOUSE (1-980): 0: 892: 98.27		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Hs
		942335 GRIK2_HUMAN (7-892): 0: 862: 43.86		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Rn
		677766 GRIK2_RAT (5-892): 0: 861: 43.65		DLG4_RAT (50-282): 1.36e-25: 115: 20.50
+	Mm
		761217 GRIK2_MOUSE (5-892): 0: 861: 43.65		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Hs
		761199 GRIK1_HUMAN (5-838): 0: 841: 43.71		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Rn
		585138 GRIA1_RAT (1-902): 0: 788: 33.77		DLG4_RAT (50-282): 1.36e-25: 115: 20.50
+	Mm
		620892 GRIA1_MOUSE (1-902): 0: 786: 33.77		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Hs
		786757 GRIA3_HUMAN (5-847): 0: 771: 35.07		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Mm
		1143565 GRIA4_MOUSE (4-878): 0: 770: 33.48		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Mm
		1143566 GRIA3_MOUSE (5-847): 0: 770: 35.07		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Mm
		620904 GRIA1_MOUSE (1-902): 0: 786: 33.77		DLG2_MOUSE (312-547): 1.48e-16: 86.4: 21.40
+	Hs
		786726 GRIA2_HUMAN (6-847): 0: 753: 34.61		DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25
+	Mm
		620965 GRIA2_MOUSE (6-847): 0: 748: 34.49		DLG4_MOUSE (50-285): 1.06e-25: 115: 20.25
+	Rn
		585186 GRIA2_RAT (6-847): 0: 748: 34.49		MPP4_RAT (130-304): 1.45e-14: 79.1: 13.83