HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: DCA11 (Q8TEB1)
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)
Gene: DCAF11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 33783207, 35271311, 37689310, 16964240, 16949367, 17079684, 28514442, 28453520, 28446751, 27203182, 31155351, 32235678, 33961781, 19295130, 19109893
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSF_A~WD40, MMS1_N~WD40
Common GO terms GO:0005654 - nucleoplasm
GO:0016567 - protein ubiquitination
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1140
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024